NMA: Network Meta-Analysis Based on Multivariate Meta-Analysis and Meta-Regression Models

Network meta-analysis tools based on contrast-based approach using the multivariate meta-analysis and meta-regression models (Noma et al. (2025) <doi:10.1101/2025.09.15.25335823>). Comprehensive analysis tools for network meta-analysis and meta-regression (e.g., synthesis analysis, ranking analysis, and creating league table) are available through simple commands. For inconsistency assessment, the local and global inconsistency tests based on the Higgins' design-by-treatment interaction model are available. In addition, the side-splitting methods and Jackson's random inconsistency model can be applied. Standard graphical tools for network meta-analysis, including network plots, ranked forest plots, and transitivity analyses, are also provided. For the synthesis analyses, the Noma-Hamura's improved REML (restricted maximum likelihood)-based methods (Noma et al. (2023) <doi:10.1002/jrsm.1652> <doi:10.1002/jrsm.1651>) are adopted as the default methods.

Version: 2.1-1
Depends: R (≥ 3.5.0)
Imports: stats, grid, MASS, ggplot2, metafor, stringr, forestplot, nleqslv
Published: 2025-09-18
DOI: 10.32614/CRAN.package.NMA
Author: Hisashi Noma ORCID iD [aut, cre], Kazushi Maruo [aut], Shiro Tanaka [aut], Toshi A. Furukawa [aut]
Maintainer: Hisashi Noma <noma at ism.ac.jp>
License: GPL-3
URL: https://doi.org/10.1101/2025.09.15.25335823
NeedsCompilation: no
Materials: NEWS
In views: MetaAnalysis
CRAN checks: NMA results

Documentation:

Reference manual: NMA.html , NMA.pdf

Downloads:

Package source: NMA_2.1-1.tar.gz
Windows binaries: r-devel: NMA_1.4-3.zip, r-release: NMA_1.4-3.zip, r-oldrel: NMA_1.4-3.zip
macOS binaries: r-release (arm64): NMA_1.4-3.tgz, r-oldrel (arm64): NMA_1.4-3.tgz, r-release (x86_64): NMA_1.4-3.tgz, r-oldrel (x86_64): NMA_1.4-3.tgz
Old sources: NMA archive

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